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Título: Frequencies of Blood Group Systems MNS, Diego, and Duffy and Clinical Phases of Carrion’s Disease in Amazonas, Peru
Autor: Acosta, Óscar
Solano, Luis
Escobar, Jorge
Fernandez, Miguel
Solano, Carlos
Fujita, Ricardo
Temas: Infecciones por Bartonella
Enfermedades endémicas
Ecosistema andino
Fecha de publicación: 2014
Lugar de publicación: Interdisciplinary Perspectives on Infectious Diseases
Citación: Oscar Acosta, Luis Solano, Jorge Escobar, Miguel Fernandez, Carlos Solano, and Ricardo Fujita, “Frequencies of Blood Group Systems MNS, Diego, and Duffy and Clinical Phases of Carrion’s Disease in Amazonas, Peru,” Interdisciplinary Perspectives on Infectious Diseases, vol. 2014, Article ID 576107, 8 pages, 2014. doi:10.1155/2014/576107
Citación: Interdisciplinary Perspectives on Infectious Diseases;vol 2014, Article ID 576107
Resumen: Carrion’s disease (CD), is a human bartonellosis, that is, endemic in the Andes of Peru, Ecuador, and Colombia. Bartonella bacilliformis, a native hemotrophic bacteria, is the causative agent of CD, and the interaction with the host could have produced changes in the gene frequencies of erythrocyte antigens.The goal here is to investigate the relationship between allele frequencies of blood group systems MNS, Diego, and Duffy and the clinical phases of CD, within a genetic context. In this associative and analytical study, 76 individuals from Bagua Grande, the province of Utcubamba, and the department of Amazonas in Peru, were enrolled. Forty of them resided in Tomocho-Collicate-Vista Hermosa area (high prevalence of cases in chronic phase, verrucous, or eruptive phase, without previous acute phase). Thirty-six individuals were from the area of Miraflores (high prevalence of cases in acute phase only) and were evaluated for blood group systems MNS, Diego, and Duffy. This study constitutes one of the first attempts at evaluating the genetic factors and clinical phases of CD. No significant statistical differences (𝑃 > 0.05) between allele frequencies of blood groups MNS, Diego, and Duffy and the prevalence of chronic and acute phases were detected in the two areas of Amazonas, Peru.
Identificador digital (URI): http://dx.doi.org/10.1155/2014/576107
http://www.repositorioacademico.usmp.edu.pe/handle/usmp/1533
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